Our Process for drug discovery
& development
Perfecting natural molecules to optimize the fight against cancer.
Utilizing the latest technologies in a proprietary process, Empath aims to efficiently discover and modify novel, selective, potent, less toxic, and scalable cancer treatments.
Mining unexplored ecosystems for new cures via layered derisking strategies
– New microbial strains isolated from unexplored ecosystems have a track record of creating novel bioactive chemical diversity.
– Genome mining, through advanced genomic analyses, can predict biosynthetic potential before searching a microbe for new bioactive compounds.
Accelerating discovery via single cell chemical biology
– A single cell discovery platform uses multiplexed simultaneous cellular assays and cell types with integrated AI analysis for discovery of new types of cancer lead chemistries.
– Lead compounds are analyzed against primary cells from patients to reveal chemistry that works in human cells, not just immortalized cell lines, with differential patient response profiles, providing significantly advanced lead compounds for human medicine.
Optimizing natural scaffolds via
(bio)synthetically modified structures
– Opportunities for reduced toxicity: widen therapeutic window and improve pharmacokinetic profile.
– Increased potency: greater therapeutic effect at reduced concentrations.
– Microbial producers can be cultivated in large scale fermentation to solve supply issues and provide green renewable routes to drugs.
